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The 16th International Conference on Software, Knowledge, Information Management and Applications (SKIMA 2025) (technically co-sponsored by IEEE Computer Society) is going to be hosted by the Artificial Intelligence, Virtual Communication and Networks (AVCN) Research Institute, University of the West of Scotland on 9-11 June, 2025 in Paisley, Scotland, UK. The conference aims to bring together researchers and experts in Knowledge Management, Software Engineering, and Information Systems to share their ideas, experiences, and insights. We welcome researchers and practitioners from academia, industries, research institutions, R&D enterprise services and governmental organisations to exchange innovative contributions around the conference topics. This conference series was started in an international collaboration context between research professionals in Western and Asian countries in Chiang Mai, Thailand 2006. Subsequently, the next SKIMA conferences were organised in Kathmandu, Nepal in 2008; Fez, Morocco in 2009; Paro, Bhutan in 2010; Benevento, Italy in 2011, Chengdu, China in 2012, Chiang Mai Thailand in 2013, Dhaka, Bangladesh in 2014, Kathmandu Nepal in 2015, Chengdu China 2016, Colombo Sri Lanka in 2017, Phnom Penh, Cambodia in 2018, Maldives 2019, Phnom Penh, Cambodia 2022 and Kuala Lumpur, Malaysia in 2023.